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The Agitation Workouts take longer to recover from

When OXY was administered, relative to the LPS group, there was a noticeable decrease in the pro-inflammatory cytokines and enhancement in the anti-inflammatory cytokine, IL-10 (Figure 2)

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Thus, two conditions are required for AG-120 efficacy against wtIDH1 tumors: 1) low Mg 2+ (to inhibit wtIDH1 activity), and 2) low nutrients (such that wtIDH1 is required for cell survival)